Quoted from: https://www.globio.info/what-is-globio
GLOBIO calculates local terrestrial biodiversity intactness, expressed by the mean species abundance (MSA) indicator, as a function of six human pressures: land use, road disturbance, fragmentation, hunting, atmospheric nitrogen deposition and climate change. The core of the model consists of quantitative pressure-impact relationships that have been established based on extensive terrestrial biodiversity databases.
GLOBIO combines the pressure–impact relationships with data on past, present or future pressure levels, typically retrieved from the IMAGE model. This results in maps with MSA values corresponding with each pressure. These maps are then combined to obtain overall MSA values, as illustrated in the figure. Next, MSA values are aggregated to larger (user-defined) regions. In addition, the contributions of the different pressures to the losses in MSA are quantified for each region.
GLOBIO also includes a routine to downscale coarse-grained land-use data to more fine-grained maps (currently with a resolution of 10 arc-seconds; ~300 m at the equator). This routine was developed because current global land‐use models have a relatively low spatial resolution hence tend to underestimate the spatial heterogeneity of land-use patterns. The downscaling routine requires regional totals or demands (‘claims’) of each land-use type and allocates these to the grid cells within the region in order of decreasing suitability for that land-use type.

To the GLOBIO 4 paper
To the GLOBIO 3.5 technical description
To the GLOBIO 3 paper